Preventing tumor progression to the bone by induced tumor-suppressing MSCs

Background: Advanced breast cancer metastasizes to many organs including bone, but few effective treatments are available. Here we report that induced tumor-suppressing (iTS) MSCs protected bone from metastases while un-induced MSCs did not. Methods: iTS MSCs were generated by overexpressing Lrp5, β...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Xun, Li, Kexin, Zha, Rongrong, Liu, Shengzhi, Fan, Yao, Wu, Di, Hase, Misato, Aryal, Uma K., Lin, Chien-Chi, Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039940/
https://www.ncbi.nlm.nih.gov/pubmed/33859739
http://dx.doi.org/10.7150/thno.58779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039940/
https://www.ncbi.nlm.nih.gov/pubmed/33859739
http://dx.doi.org/10.7150/thno.58779

Ejemplares similares