HDAC1 and 2 regulate endothelial VCAM-1 expression and atherogenesis by suppressing methylation of the GATA6 promoter

Increased expression of vascular cell adhesion molecule (VCAM)-1 on the activated arterial endothelial cell (EC) surface critically contributes to atherosclerosis which may in part be regulated by epigenetic mechanisms. This study investigated whether and how the clinically available histone deacety...

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Detalles Bibliográficos
Autores principales: Hu, Chengxiu, Peng, Kai, Wu, Qianqian, Wang, Yiying, Fan, Xing, Zhang, Dai-Min, Passerini, Anthony G., Sun, ChongXiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039941/
https://www.ncbi.nlm.nih.gov/pubmed/33859766
http://dx.doi.org/10.7150/thno.55878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039941/
https://www.ncbi.nlm.nih.gov/pubmed/33859766
http://dx.doi.org/10.7150/thno.55878

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