c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation

Rationale: NRF2, a redox sensitive transcription factor, is up-regulated in head and neck squamous cell carcinoma (HNSCC), however, the associated impact and regulatory mechanisms remain unclear. Methods: The protein expression of NRF2 in HNSCC specimens was examined by IHC. The regulatory effect of...

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Detalles Bibliográficos
Autores principales: Tang, Ya-Chu, Hsiao, Jenn-Ren, Jiang, Shih-Sheng, Chang, Jang-Yang, Chu, Pei-Yi, Liu, Ko-Jiunn, Fang, Hsun-Lang, Lin, Li-Mei, Chen, Huang-Hui, Huang, Yen-Wen, Chen, Yu-Tsen, Tsai, Fang-Yu, Lin, Su-Fang, Chuang, Yung-Jen, Kuo, Ching-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039948/
https://www.ncbi.nlm.nih.gov/pubmed/33859744
http://dx.doi.org/10.7150/thno.53417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039948/
https://www.ncbi.nlm.nih.gov/pubmed/33859744
http://dx.doi.org/10.7150/thno.53417

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