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An integrated epigenomic-transcriptomic landscape of lung cancer reveals novel methylation driver genes of diagnostic and therapeutic relevance

Background: Aberrant DNA methylation occurs commonly during carcinogenesis and is of clinical value in human cancers. However, knowledge of the impact of DNA methylation changes on lung carcinogenesis and progression remains limited. Methods: Genome-wide DNA methylation profiles were surveyed in 18...

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Detalles Bibliográficos
Autores principales: Sun, Xiwei, Yi, Jiani, Yang, Juze, Han, Yi, Qian, Xinyi, Liu, Yi, Li, Jia, Lu, Bingjian, Zhang, Jisong, Pan, Xiaoqing, Liu, Yong, Liang, Mingyu, Chen, Enguo, Liu, Pengyuan, Lu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039961/
https://www.ncbi.nlm.nih.gov/pubmed/33859751
http://dx.doi.org/10.7150/thno.58385