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The combined induction of liver progenitor cells and the suppression of stellate cells by small molecules reverts chronic hepatic dysfunction

Rationale: We developed a cocktail of soluble molecules mimicking the in vivo milieu supporting liver regeneration that could convert mature hepatocytes to expandable liver progenitor-like cells in vitro. This study aimed to induce endogenous liver progenitor cells by the administration of the solub...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Jian, Zhou, Xu, Fu, Gong-Bo, Ding, Min, Wu, Hong-Ping, Zeng, Min, Zhang, Hong-Dan, Xu, Ling-Yan, Gao, Yi, Wang, Hong-Yang, Yan, He-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039967/
https://www.ncbi.nlm.nih.gov/pubmed/33859762
http://dx.doi.org/10.7150/thno.54457