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Vascular endothelial growth factor B inhibits insulin secretion in MIN6 cells and reduces Ca(2+) and cyclic adenosine monophosphate levels through PI3K/AKT pathway

BACKGROUND: Type 2 diabetes (T2D) is characterized by insufficient insulin secretion caused by defective pancreatic β-cell function or insulin resistance, resulting in an increase in blood glucose. However, the mechanism involved in this lack of insulin secretion is unclear. The level of vascular en...

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Detalles Bibliográficos
Autores principales: Jia, Jing-Dan, Jiang, Wen-Guo, Luo, Xu, Li, Rong-Rong, Zhao, Yu-Chi, Tian, Geng, Li, Ya-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040075/
https://www.ncbi.nlm.nih.gov/pubmed/33889292
http://dx.doi.org/10.4239/wjd.v12.i4.480