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Vascular endothelial growth factor B inhibits insulin secretion in MIN6 cells and reduces Ca(2+) and cyclic adenosine monophosphate levels through PI3K/AKT pathway
BACKGROUND: Type 2 diabetes (T2D) is characterized by insufficient insulin secretion caused by defective pancreatic β-cell function or insulin resistance, resulting in an increase in blood glucose. However, the mechanism involved in this lack of insulin secretion is unclear. The level of vascular en...
Autores principales: | Jia, Jing-Dan, Jiang, Wen-Guo, Luo, Xu, Li, Rong-Rong, Zhao, Yu-Chi, Tian, Geng, Li, Ya-Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040075/ https://www.ncbi.nlm.nih.gov/pubmed/33889292 http://dx.doi.org/10.4239/wjd.v12.i4.480 |
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