Hypothermia Protects Mice Against Ischemic Stroke by Modulating Macrophage Polarization Through Upregulation of Interferon Regulatory Factor-4

BACKGROUND: Therapeutic hypothermia (TH) has been proven to be protective in ischemic stroke (IS) due to its anti-inflammatory capacity. Recently, the interferon regulatory factor 4 (IRF4) has been characterized as a central regulator of neuroinflammation in IS. Here we aim to determine whether IFR4...

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Detalles Bibliográficos
Autores principales: Yu, Xinyuan, Feng, Yanping, Liu, Renzhong, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040092/
https://www.ncbi.nlm.nih.gov/pubmed/33854355
http://dx.doi.org/10.2147/JIR.S303053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040092/
https://www.ncbi.nlm.nih.gov/pubmed/33854355
http://dx.doi.org/10.2147/JIR.S303053

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