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Screening neutral sites for metabolic engineering of methylotrophic yeast Ogataea polymorpha

Methylotrophic yeast Ogataea polymorpha is capable to utilize multiple carbon feedstocks especially methanol as sole carbon source and energy, making it an ideal host for bio-manufacturing. However, the lack of gene integration sites limits its systems metabolic engineering, in particular constructi...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Gao, Jiaoqi, Zhai, Xiaoxin, Zhou, Yongjin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040119/
https://www.ncbi.nlm.nih.gov/pubmed/33869812
http://dx.doi.org/10.1016/j.synbio.2021.03.001