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Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer patients

BACKGROUND: Colorectal cancer (CRC) is common in elderly patients. Mismatch repair (MMR) protein deletion is one of the causes of CRC. The RAS (KRAS/NRAS), BRAF, and PIK3CA genes are important gene targets in CRC treatment and are closely related to the prognosis and survival of patients. However, l...

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Detalles Bibliográficos
Autores principales: Fan, Jun-Zhen, Wang, Gao-Fei, Cheng, Xue-Bin, Dong, Zhou-Huan, Chen, Xin, Deng, Yu-Jiao, Song, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040173/
https://www.ncbi.nlm.nih.gov/pubmed/33889611
http://dx.doi.org/10.12998/wjcc.v9.i11.2458