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Computational methods for chromosome-scale haplotype reconstruction
High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid genomes, and metagenomes provide important insights into genetic variation associated with disease and biodiversity. However, whole-genome short read sequencing does not yield haplotype information spanning whole chromos...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040228/ https://www.ncbi.nlm.nih.gov/pubmed/33845884 http://dx.doi.org/10.1186/s13059-021-02328-9 |