PLK1-mediated S369 phosphorylation of RIPK3 during G2 and M phases enables its ripoptosome incorporation and activity

Receptor-interacting protein kinase 3 executes a form of regulated necrosis called necroptosis. Upon induction of an altered conformation by chemical inhibitors or via mutations in its kinase site, RIPK3 associates with a multiprotein complex called the ripoptosome—a signaling platform containing FA...

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Detalles Bibliográficos
Autores principales: Gupta, Kartik, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040267/
https://www.ncbi.nlm.nih.gov/pubmed/33870135
http://dx.doi.org/10.1016/j.isci.2021.102320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040267/
https://www.ncbi.nlm.nih.gov/pubmed/33870135
http://dx.doi.org/10.1016/j.isci.2021.102320

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