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Identification and functional characterization of a Siglec-7 counter-receptor on K562 cells

Sialic acid (Sia)-binding immunoglobulin-like lectin 7 (Siglec-7) is an inhibitory receptor primarily expressed on natural killer (NK) cells and monocytes. Siglec-7 is known to negatively regulate the innate immune system through Sia binding to distinguish self and nonself; however, a counter-recept...

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Detalles Bibliográficos
Autores principales: Yoshimura, Atsushi, Asahina, Yuki, Chang, Lan-Yi, Angata, Takashi, Tanaka, Hiroshi, Kitajima, Ken, Sato, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040268/
https://www.ncbi.nlm.nih.gov/pubmed/33640457
http://dx.doi.org/10.1016/j.jbc.2021.100477