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Genistein-3′-sodium sulfonate Attenuates Neuroinflammation in Stroke Rats by Down-Regulating Microglial M1 Polarization through α7nAChR-NF-κB Signaling Pathway

Microglial M1 depolarization mediated prolonged inflammation contributing to brain injury in ischemic stroke. Our previous study revealed that Genistein-3′-sodium sulfonate (GSS) exerted neuroprotective effects in ischemic stroke. This study aimed to explore whether GSS protected against brain injur...

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Detalles Bibliográficos
Autores principales: Liu, Chaoming, Liu, Song, Xiong, Lijiao, Zhang, Limei, Li, Xiao, Cao, Xingling, Xue, Jinhua, Li, Liangdong, Huang, Cheng, Huang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040300/
https://www.ncbi.nlm.nih.gov/pubmed/33867831
http://dx.doi.org/10.7150/ijbs.56800