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Isochromanoindolenines suppress triple-negative breast cancer cell proliferation partially via inhibiting Akt activation
As the most malignant subtype of breast cancers, triple-negative breast cancer (TNBC) lacks effective targeted therapeutics clinically to date. In this study, one lead compound FZU-0025-065 with isochromanoindolenine scaffold was identified by a cell-based screening. Among nine breast cancer cell li...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040301/ https://www.ncbi.nlm.nih.gov/pubmed/33867823 http://dx.doi.org/10.7150/ijbs.48170 |