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Isochromanoindolenines suppress triple-negative breast cancer cell proliferation partially via inhibiting Akt activation

As the most malignant subtype of breast cancers, triple-negative breast cancer (TNBC) lacks effective targeted therapeutics clinically to date. In this study, one lead compound FZU-0025-065 with isochromanoindolenine scaffold was identified by a cell-based screening. Among nine breast cancer cell li...

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Detalles Bibliográficos
Autores principales:	Jiang, Xiaoyan, Zhi, Xu, Zhang, Peixia, Zhou, Zhongmei, Ye, Jinxiang, Gao, Yu, Wang, Xinye, Yang, Chuanyu, Chen, Haijun, Liu, Rong, Chen, Ceshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040301/ https://www.ncbi.nlm.nih.gov/pubmed/33867823 http://dx.doi.org/10.7150/ijbs.48170

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