Integrin Activation Enables Sensitive Detection of Functional CD4(+) and CD8(+) T Cells: Application to Characterize SARS-CoV-2 Immunity

We have previously shown that conformational change in the β(2)-integrin is a very early activation marker that can be detected with fluorescent multimers of its ligand intercellular adhesion molecule (ICAM)-1 for rapid assessment of antigen-specific CD8(+) T cells. In this study, we describe a modi...

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Detalles Bibliográficos
Autores principales: Schöllhorn, Anna, Schuhmacher, Juliane, Besedovsky, Luciana, Fendel, Rolf, Jensen, Anja T. R., Stevanović, Stefan, Lange, Tanja, Rammensee, Hans-Georg, Born, Jan, Gouttefangeas, Cécile, Dimitrov, Stoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040333/
https://www.ncbi.nlm.nih.gov/pubmed/33854501
http://dx.doi.org/10.3389/fimmu.2021.626308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040333/
https://www.ncbi.nlm.nih.gov/pubmed/33854501
http://dx.doi.org/10.3389/fimmu.2021.626308

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