Cargando…

Integrin Activation Enables Sensitive Detection of Functional CD4(+) and CD8(+) T Cells: Application to Characterize SARS-CoV-2 Immunity

We have previously shown that conformational change in the β(2)-integrin is a very early activation marker that can be detected with fluorescent multimers of its ligand intercellular adhesion molecule (ICAM)-1 for rapid assessment of antigen-specific CD8(+) T cells. In this study, we describe a modi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schöllhorn, Anna, Schuhmacher, Juliane, Besedovsky, Luciana, Fendel, Rolf, Jensen, Anja T. R., Stevanović, Stefan, Lange, Tanja, Rammensee, Hans-Georg, Born, Jan, Gouttefangeas, Cécile, Dimitrov, Stoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040333/ https://www.ncbi.nlm.nih.gov/pubmed/33854501 http://dx.doi.org/10.3389/fimmu.2021.626308

Ejemplares similares

Activated integrins identify functional antigen-specific CD8(+) T cells within minutes after antigen stimulation
por: Dimitrov, Stoyan, et al.
Publicado: (2018)

Staining of activated ß(2)-integrins in combination with CD137 and CD154 for sensitive identification of functional antigen-specific CD4(+) and CD8(+) T cells
por: Schöllhorn, Anna, et al.
Publicado: (2023)

Gα(s)-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells
por: Dimitrov, Stoyan, et al.
Publicado: (2019)

CD4+ T Cells: Multitasking Cells in the Duty of Cancer Immunotherapy
por: Richardson, Jennifer R., et al.
Publicado: (2021)

Simultaneous Identification of Functional Antigen-Specific CD8(+) and CD4(+) Cells after In Vitro Expansion Using Elongated Peptides
por: Schuhmacher, Juliane, et al.
Publicado: (2022)

CAF-immune cell crosstalk and its impact in immunotherapy
por: Maia, Ana, et al.
Publicado: (2022)

Mineralocorticoid receptor signaling reduces numbers of circulating human naïve T cells and increases their CD62L, CCR7, and CXCR4 expression
por: Besedovsky, Luciana, et al.
Publicado: (2014)

Sleep and immune function
por: Besedovsky, Luciana, et al.
Publicado: (2011)

Blocking Mineralocorticoid Receptors Impairs, Blocking Glucocorticoid Receptors Enhances Memory Retrieval in Humans
por: Rimmele, Ulrike, et al.
Publicado: (2013)

Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function
por: Besedovsky, Luciana, et al.
Publicado: (2017)

The Sleep-Immune Crosstalk in Health and Disease
por: Besedovsky, Luciana, et al.
Publicado: (2019)

The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic
por: Lange, Tanja, et al.
Publicado: (2022)

Induction of Atrial Fibrillation by Neutrophils Critically Depends on CD11b/CD18 Integrins
por: Friedrichs, Kai, et al.
Publicado: (2014)

Broad and Efficient Activation of Memory CD4(+) T Cells by Novel HAdV- and HCMV-Derived Peptide Pools
por: Höttler, Alexander, et al.
Publicado: (2021)

Vaccination against RhoC induces long-lasting immune responses in patients with prostate cancer: results from a phase I/II clinical trial
por: Schuhmacher, Juliane, et al.
Publicado: (2020)

Human sleep consolidates allergic responses conditioned to the environmental context of an allergen exposure
por: Besedovsky, Luciana, et al.
Publicado: (2020)

Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy
por: Mu, Lingmin, et al.
Publicado: (2014)

Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18 †
por: Díaz-Alvarez, Laura, et al.
Publicado: (2023)

More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer
por: Haen, Sebastian P., et al.
Publicado: (2011)

Hypnotic enhancement of slow-wave sleep increases sleep-associated hormone secretion and reduces sympathetic predominance in healthy humans
por: Besedovsky, Luciana, et al.
Publicado: (2022)

Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1)
Publicado: (1995)

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer
por: Chen, Wei-Ching, et al.
Publicado: (2015)

Cytokines and TLR agonists influence the expression of retention integrins CD49a, CD49b and CD103 by T cells
por: Melssen, Marit M, et al.
Publicado: (2015)

Molecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificity
por: Trstenjak, Nikolina, et al.
Publicado: (2020)

The Colocalization Potential of HIV-Specific CD8(+) and CD4(+) T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid
por: Wacleche, Vanessa Sue, et al.
Publicado: (2012)

CD93 promotes β(1) integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
por: Lugano, Roberta, et al.
Publicado: (2018)

Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β(2) Integrin CD11b/CD18
por: Golshani, Maryam, et al.
Publicado: (2022)

A peptide derived from the intercellular adhesion molecule-2 regulates the avidity of the leukocyte integrins CD11b/CD18 and CD11c/CD18
Publicado: (1995)

Adipocytes in their (CD)40s
por: Bertola, Adeline, et al.
Publicado: (2023)

A Simple and Rapid Method for Quality Control of Major Histocompatibility Complex–Peptide Monomers by Flow Cytometry
por: Chandran, P. Anoop, et al.
Publicado: (2017)

Radiotherapy planning parameters correlate with changes in the peripheral immune status of patients undergoing curative radiotherapy for localized prostate cancer
por: Hoffmann, Elgin, et al.
Publicado: (2021)

Integrin-independent support of cancer drug resistance by tetraspanin CD151
por: Hwang, Soonyean, et al.
Publicado: (2019)

Integrin α(E)(CD103)β(7) in Epithelial Cancer
por: Hoffmann, Johanna C., et al.
Publicado: (2021)

Novel Functions of Integrins as Receptors of CD154: Their Role in Inflammation and Apoptosis
por: Hassan, Ghada S., et al.
Publicado: (2022)

Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma
por: Bilich, Tatjana, et al.
Publicado: (2020)

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins
Publicado: (1989)

Platelet Glycoprotein Ibα Is a Counterreceptor for the Leukocyte Integrin Mac-1 (Cd11b/Cd18)
por: Simon, Daniel I., et al.
Publicado: (2000)

Costimulation of T Cell Activation by Integrin-associated Protein (CD47) Is an Adhesion-dependent, CD28-independent Signaling Pathway
por: Reinhold, Martina I., et al.
Publicado: (1997)

Profiling of the Tetraspanin CD151 Web and Conspiracy of CD151/Integrin β1 Complex in the Progression of Hepatocellular Carcinoma
por: Devbhandari, Ranjan Prasad, et al.
Publicado: (2011)

β2 Integrin CD11d/CD18: From Expression to an Emerging Role in Staged Leukocyte Migration
por: Blythe, Eoin N., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iqsijhck0ha99hggjrnovtlkr8