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Virtual screening by targeting proteolytic sites of furin and TMPRSS2 to propose potential compounds obstructing the entry of SARS-CoV-2 virus into human host cells

BACKGROUND AND AIM: The year 2020 begins with the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that cause the disease COVID-19, and continue till today. As of March 23, 2021, the outbreak has infected 124,313,054 worldwide with a total death of 2,735,707. The use of tradi...

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Detalles Bibliográficos
Autores principales: Vardhan, Seshu, Sahoo, Suban K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040387/
https://www.ncbi.nlm.nih.gov/pubmed/33868970
http://dx.doi.org/10.1016/j.jtcme.2021.04.001