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Characteristics and prognostic value of potential dependency genes in clear cell renal cell carcinoma based on a large-scale CRISPR-Cas9 and RNAi screening database DepMap

Background: Large-scale loss-of-function screening database such as Cancer Dependency Map (Depmap) provide abundant resources. Investigation of these potential dependency genes from human cancer cell lines in the real-world patients cohort would evaluate their prognostic value thus facilitate their...

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Detalles Bibliográficos
Autores principales: Shi, Bowen, Ding, Jie, Qi, Jun, Gu, Zhengqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040392/
https://www.ncbi.nlm.nih.gov/pubmed/33850477
http://dx.doi.org/10.7150/ijms.51703