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Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis

HLA-F, a nonclassical HLA class I molecule, is required for regulating immune tolerance. In recent years, HLA-F has been found to play a role in a variety of cancers, including glioma (GM). Additionally, high expression of HLA-F predicts the poor overall survival of individuals with GM. However, the...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Sun, Na, Li, Rongqin, Sang, Xuejia, Li, Xueqin, Zhao, Jie, Han, Jing, Yang, Jing, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040476/
https://www.ncbi.nlm.nih.gov/pubmed/33867844
http://dx.doi.org/10.7150/ijbs.56357