Moderate mechanical stimulation rescues degenerative annulus fibrosus by suppressing caveolin-1 mediated pro-inflammatory signaling pathway

Mechanical loading can induce or antagonize the extracellular matrix (ECM) synthesis, proliferation, migration, and inflammatory responses of annulus fibrosus cells (AFCs), depending on the loading mode and level. Caveolin-1 (Cav1), the core protein of caveolae, plays an important role in cellular m...

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Detalles Bibliográficos
Autores principales: Zhang, Weidong, Wang, Huan, Yuan, Zhangqin, Chu, Genglei, Sun, Heng, Yu, Zilin, Liang, Huan, Liu, Tao, Zhou, Feng, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040478/
https://www.ncbi.nlm.nih.gov/pubmed/33867854
http://dx.doi.org/10.7150/ijbs.57774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040478/
https://www.ncbi.nlm.nih.gov/pubmed/33867854
http://dx.doi.org/10.7150/ijbs.57774

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