Cargando…
Moderate mechanical stimulation rescues degenerative annulus fibrosus by suppressing caveolin-1 mediated pro-inflammatory signaling pathway
Mechanical loading can induce or antagonize the extracellular matrix (ECM) synthesis, proliferation, migration, and inflammatory responses of annulus fibrosus cells (AFCs), depending on the loading mode and level. Caveolin-1 (Cav1), the core protein of caveolae, plays an important role in cellular m...
Autores principales: | Zhang, Weidong, Wang, Huan, Yuan, Zhangqin, Chu, Genglei, Sun, Heng, Yu, Zilin, Liang, Huan, Liu, Tao, Zhou, Feng, Li, Bin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040478/ https://www.ncbi.nlm.nih.gov/pubmed/33867854 http://dx.doi.org/10.7150/ijbs.57774 |
Ejemplares similares
-
Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds
por: Zhou, Pinghui, et al.
Publicado: (2020) -
Strategies for Annulus Fibrosus Regeneration: From Biological Therapies to Tissue Engineering
por: Chu, Genglei, et al.
Publicado: (2018) -
TGF-β1-supplemented decellularized annulus fibrosus matrix hydrogels promote annulus fibrosus repair
por: Wei, Qiang, et al.
Publicado: (2022) -
Single-cell RNA sequencing reveals resident progenitor and vascularization-associated cell subpopulations in rat annulus fibrosus
por: Sun, Heng, et al.
Publicado: (2022) -
Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model
por: Nukaga, Tadashi, et al.
Publicado: (2019)