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Low-Dose Interleukin-2 and Regulatory T Cell Treatments Attenuate Punctate and Dynamic Mechanical Allodynia in a Mouse Model of Sciatic Nerve Injury

PURPOSE: Nerve injury-induced mechanical hyper-sensitivity, in particular stroking-induced dynamic allodynia, is highly debilitating and difficult to treat. Previous studies indicate that the immunosuppressive regulatory T (Treg) cells modulate the magnitude of punctate mechanical allodynia resultin...

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Detalles Bibliográficos
Autores principales: Hu, Rong, Zhang, Jintao, Liu, Xuemei, Huang, Dong, Cao, Yu-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040486/
https://www.ncbi.nlm.nih.gov/pubmed/33854366
http://dx.doi.org/10.2147/JPR.S301343