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Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation

Antimalarial antibody responses are essential for mediating the clearance of Plasmodium parasite–infected RBCs from infected hosts. However, the rapid appearance of large numbers of plasmablasts in Plasmodium-infected hosts can suppress the development and function of durable humoral immunity. Here,...

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Detalles Bibliográficos
Autores principales: Vijay, Rahul, Guthmiller, Jenna J., Sturtz, Alexandria J., Crooks, Sequoia, Johnson, Jordan T., Li, Lei, Lan, Linda Yu-Ling, Pope, Rosemary L., Chen, Yani, Rogers, Kai J., Dutta, Nirmal, Toombs, Jason E., Wilson, Mary E., Wilson, Patrick C., Maury, Wendy, Brekken, Rolf A., Butler, Noah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040514/
https://www.ncbi.nlm.nih.gov/pubmed/33830176
http://dx.doi.org/10.1084/jem.20202359