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Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease

Tick-borne encephalitis virus (TBEV) is an emerging human pathogen that causes potentially fatal disease with no specific treatment. Mouse monoclonal antibodies are protective against TBEV, but little is known about the human antibody response to infection. Here, we report on the human neutralizing...

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Detalles Bibliográficos
Autores principales: Agudelo, Marianna, Palus, Martin, Keeffe, Jennifer R., Bianchini, Filippo, Svoboda, Pavel, Salát, Jiří, Peace, Avery, Gazumyan, Anna, Cipolla, Melissa, Kapoor, Tania, Guidetti, Francesca, Yao, Kai-Hui, Elsterová, Jana, Teislerová, Dana, Chrdle, Aleš, Hönig, Václav, Oliveira, Thiago, West, Anthony P., Lee, Yu E., Rice, Charles M., MacDonald, Margaret R., Bjorkman, Pamela J., Růžek, Daniel, Robbiani, Davide F., Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040517/
https://www.ncbi.nlm.nih.gov/pubmed/33831141
http://dx.doi.org/10.1084/jem.20210236