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Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease
Tick-borne encephalitis virus (TBEV) is an emerging human pathogen that causes potentially fatal disease with no specific treatment. Mouse monoclonal antibodies are protective against TBEV, but little is known about the human antibody response to infection. Here, we report on the human neutralizing...
Autores principales: | Agudelo, Marianna, Palus, Martin, Keeffe, Jennifer R., Bianchini, Filippo, Svoboda, Pavel, Salát, Jiří, Peace, Avery, Gazumyan, Anna, Cipolla, Melissa, Kapoor, Tania, Guidetti, Francesca, Yao, Kai-Hui, Elsterová, Jana, Teislerová, Dana, Chrdle, Aleš, Hönig, Václav, Oliveira, Thiago, West, Anthony P., Lee, Yu E., Rice, Charles M., MacDonald, Margaret R., Bjorkman, Pamela J., Růžek, Daniel, Robbiani, Davide F., Nussenzweig, Michel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040517/ https://www.ncbi.nlm.nih.gov/pubmed/33831141 http://dx.doi.org/10.1084/jem.20210236 |
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