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Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome
Quality control requires discrimination between functional and aberrant species to selectively target aberrant substrates for destruction. Nuclear RNA quality control in Saccharomyces cerevisiae includes the TRAMP complex that marks RNA for decay via polyadenylation followed by helicase-dependent 3′...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040639/ https://www.ncbi.nlm.nih.gov/pubmed/33782132 http://dx.doi.org/10.1073/pnas.2024846118 |