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Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics

PIM2 (proviral integration site for Moloney murine leukemia virus 2) kinase plays an important role as an oncogene in multiple cancers, such as leukemia, liver, lung, myeloma, prostate and breast cancers. PIM2 is largely expressed in both leukemia and solid tumors, and it promotes the transcriptiona...

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Detalles Bibliográficos
Autores principales: Wang, Yixin, Xiu, Jing, Ren, Chune, Yu, Zhenhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040705/
https://www.ncbi.nlm.nih.gov/pubmed/33854618
http://dx.doi.org/10.7150/jca.53134