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Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics against Mycobacterium leprae and Mycobacterium lepromatosis

BACKGROUND: Mycobacterium leprae and Mycobacterium lepromatosis are gram-positive bacterial pathogens and the causative agents of leprosy in humans across the world. The elimination of leprosy cannot be achieved by multidrug therapy alone, and highlights the need for new tools and drugs to prevent t...

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Detalles Bibliográficos
Autores principales: Jaiswal, Arun Kumar, Tiwari, Sandeep, Jamal, Syed Babar, Oliveira, Letícia de Castro, Sales-Campos, Helioswilton, Andrade-Silva, Leonardo Eurípedes, Oliveira, Carlo Jose Freire, Ghosh, Preetam, Barh, Debmalya, Azevedo, Vasco, Soares, Siomar C., Rodrigues, Virmondes Rodrigues, da Silva, Marcos Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040911/
https://www.ncbi.nlm.nih.gov/pubmed/33889182
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0027