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Unraveling Heterogeneity of Tumor Cells and Microenvironment and Its Clinical Implications for Triple Negative Breast Cancer

Objective: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer, characterized by extensive intratumoral heterogeneity. We aimed to systematically characterize the tumor heterogeneity of TNBC. Methods: Single-cell RNA sequencing (scRNA-seq) of TNBC cells were obtained from...

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Detalles Bibliográficos
Autores principales: Jiang, Ke, Dong, Mengting, Li, Chunyang, Sheng, Jiayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040954/
https://www.ncbi.nlm.nih.gov/pubmed/33854958
http://dx.doi.org/10.3389/fonc.2021.557477