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NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient prognosis. A cellular stress response mechanism called the unfolded protein response (UPR) has been implicated in PDAC progression. More recently, nucleobindin 1 (NUCB1), a calcium-binding protein, has been shown...

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Detalles Bibliográficos
Autores principales: Hua, Yong-Qiang, Zhang, Ke, Sheng, Jie, Ning, Zhou-Yu, Li, Ye, Shi, Wei-dong, Liu, Lu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041069/
https://www.ncbi.nlm.nih.gov/pubmed/33855021
http://dx.doi.org/10.3389/fcell.2021.641836