Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study

BACKGROUND: Common genetic variation in the arsenic methyltransferase (AS3MT) gene region is known to be associated with arsenic metabolism efficiency (AME), measured as the percentage of dimethylarsinic acid (DMA%) in the urine. Rare, protein-altering variants in AS3MT could have even larger effect...

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Detalles Bibliográficos
Autores principales: Delgado, Dayana A., Chernoff, Meytal, Huang, Lei, Tong, Lin, Chen, Lin, Jasmine, Farzana, Shinkle, Justin, Cole, Shelley A., Haack, Karin, Kent, Jack, Umans, Jason, Best, Lyle G., Nelson, Heather, Griend, Donald Vander, Graziano, Joseph, Kibriya, Muhammad G., Navas-Acien, Ana, Karagas, Margaret R., Ahsan, Habibul, Pierce, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041273/
https://www.ncbi.nlm.nih.gov/pubmed/33826413
http://dx.doi.org/10.1289/EHP8152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041273/
https://www.ncbi.nlm.nih.gov/pubmed/33826413
http://dx.doi.org/10.1289/EHP8152

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