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Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study
BACKGROUND: Common genetic variation in the arsenic methyltransferase (AS3MT) gene region is known to be associated with arsenic metabolism efficiency (AME), measured as the percentage of dimethylarsinic acid (DMA%) in the urine. Rare, protein-altering variants in AS3MT could have even larger effect...
Autores principales: | Delgado, Dayana A., Chernoff, Meytal, Huang, Lei, Tong, Lin, Chen, Lin, Jasmine, Farzana, Shinkle, Justin, Cole, Shelley A., Haack, Karin, Kent, Jack, Umans, Jason, Best, Lyle G., Nelson, Heather, Griend, Donald Vander, Graziano, Joseph, Kibriya, Muhammad G., Navas-Acien, Ana, Karagas, Margaret R., Ahsan, Habibul, Pierce, Brandon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041273/ https://www.ncbi.nlm.nih.gov/pubmed/33826413 http://dx.doi.org/10.1289/EHP8152 |
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