Selective CRAF Inhibition Elicits Transactivation

[Image: see text] Discovering molecules that regulate closely related protein isoforms is challenging, and in many cases the consequences of isoform-specific pharmacological regulation remains unknown. RAF isoforms are commonly mutated oncogenes that serve as effector kinases in MAP kinase signaling...

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Detalles Bibliográficos
Autores principales: Morgan, Charles W., Dale, Ian L., Thomas, Andrew P., Hunt, James, Chin, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041278/
https://www.ncbi.nlm.nih.gov/pubmed/33750116
http://dx.doi.org/10.1021/jacs.0c11958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041278/
https://www.ncbi.nlm.nih.gov/pubmed/33750116
http://dx.doi.org/10.1021/jacs.0c11958

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