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Selective CRAF Inhibition Elicits Transactivation
[Image: see text] Discovering molecules that regulate closely related protein isoforms is challenging, and in many cases the consequences of isoform-specific pharmacological regulation remains unknown. RAF isoforms are commonly mutated oncogenes that serve as effector kinases in MAP kinase signaling...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041278/ https://www.ncbi.nlm.nih.gov/pubmed/33750116 http://dx.doi.org/10.1021/jacs.0c11958 |