Halogen Atoms in the Protein–Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2

[Image: see text] Binding of a family of brominated benzotriazoles to the catalytic subunit of human protein kinase CK2 (hCK2α) was used as a model system to assess the contribution of halogen bonding to protein–ligand interaction. CK2 is a constitutively active pleiotropic serine/threonine protein...

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Detalles Bibliográficos
Autores principales: Czapinska, Honorata, Winiewska-Szajewska, Maria, Szymaniec-Rutkowska, Anna, Piasecka, Anna, Bochtler, Matthias, Poznański, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041304/
https://www.ncbi.nlm.nih.gov/pubmed/33689348
http://dx.doi.org/10.1021/acs.jpcb.0c10264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041304/
https://www.ncbi.nlm.nih.gov/pubmed/33689348
http://dx.doi.org/10.1021/acs.jpcb.0c10264

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