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Effect of Buffer on Protein Stability in Aqueous Solutions: A Simple Protein Aggregation Model

[Image: see text] Liquid–liquid phase separation (LLPS) of proteins has recently been associated with the onset of numerous diseases. Despite several studies in this area of protein aggregation, buffer-specific effects always seem to be overlooked. In this study we investigated the influence of buff...

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Detalles Bibliográficos
Autores principales: Brudar, Sandi, Hribar-Lee, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041305/
https://www.ncbi.nlm.nih.gov/pubmed/33656887
http://dx.doi.org/10.1021/acs.jpcb.0c10339