C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors

[Image: see text] Based on literature reports of the last two decades, a computer-aided pattern analysis (C@PA) was implemented for the discovery of novel multitarget ABCB1 (P-gp), ABCC1 (MRP1), and ABCG2 (BCRP) inhibitors. C@PA included basic scaffold identification, substructure search and statist...

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Detalles Bibliográficos
Autores principales: Namasivayam, Vigneshwaran, Silbermann, Katja, Wiese, Michael, Pahnke, Jens, Stefan, Sven Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041314/
https://www.ncbi.nlm.nih.gov/pubmed/33724808
http://dx.doi.org/10.1021/acs.jmedchem.0c02199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041314/
https://www.ncbi.nlm.nih.gov/pubmed/33724808
http://dx.doi.org/10.1021/acs.jmedchem.0c02199

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