Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study

BACKGROUND: Emergence of variants with specific mutations in key epitopes in the spike protein of SARS-CoV-2 raises concerns pertinent to mass vaccination campaigns and use of monoclonal antibodies. We aimed to describe the emergence of the B.1.1.7 variant of concern (VOC), including virological cha...

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Detalles Bibliográficos
Autores principales: Frampton, Dan, Rampling, Tommy, Cross, Aidan, Bailey, Heather, Heaney, Judith, Byott, Matthew, Scott, Rebecca, Sconza, Rebecca, Price, Joseph, Margaritis, Marios, Bergstrom, Malin, Spyer, Moira J, Miralhes, Patricia B, Grant, Paul, Kirk, Stuart, Valerio, Chris, Mangera, Zaheer, Prabhahar, Thaventhran, Moreno-Cuesta, Jeronimo, Arulkumaran, Nish, Singer, Mervyn, Shin, Gee Yen, Sanchez, Emilie, Paraskevopoulou, Stavroula M, Pillay, Deenan, McKendry, Rachel A, Mirfenderesky, Mariyam, Houlihan, Catherine F, Nastouli, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041359/
https://www.ncbi.nlm.nih.gov/pubmed/33857406
http://dx.doi.org/10.1016/S1473-3099(21)00170-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041359/
https://www.ncbi.nlm.nih.gov/pubmed/33857406
http://dx.doi.org/10.1016/S1473-3099(21)00170-5

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