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One Plus One Makes Three: Triangular Coupling of Correlated Amino Acid Mutations

[Image: see text] Correlated mutations have played a pivotal role in the recent success in protein fold prediction. Understanding nonadditive effects of mutations is crucial for altering protein structure, as mutations of multiple residues may change protein stability or binding affinity in a manner...

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Detalles Bibliográficos
Autores principales: Werner, Martin, Gapsys, Vytautas, de Groot, Bert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041375/
https://www.ncbi.nlm.nih.gov/pubmed/33760609
http://dx.doi.org/10.1021/acs.jpclett.1c00380