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Substrates Modulate Charge-Reorganization Allosteric Effects in Protein–Protein Association
[Image: see text] Protein function may be modulated by an event occurring far away from the functional site, a phenomenon termed allostery. While classically allostery involves conformational changes, we recently observed that charge redistribution within an antibody can also lead to an allosteric e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041378/ https://www.ncbi.nlm.nih.gov/pubmed/33710900 http://dx.doi.org/10.1021/acs.jpclett.1c00437 |