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Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition

BACKGROUND: Inhibition of acetylcholinesterase (AChE), a biomarker of organophosphorous and carbamate exposure in environmental and occupational human health, has been commonly used to identify potential safety liabilities. So far, many environmental chemicals, including drug candidates, food additi...

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Detalles Bibliográficos
Autores principales: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Travers, Jameson, Klumpp-Thomas, Carleen, Yu, Wenbo, MacKerell, Alexander D., Sakamuru, Srilatha, Ooka, Masato, Xue, Fengtian, Sipes, Nisha S., Hsieh, Jui-Hua, Ryan, Kristen, Simeonov, Anton, Santillo, Michael F., Xia, Menghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041433/
https://www.ncbi.nlm.nih.gov/pubmed/33844597
http://dx.doi.org/10.1289/EHP6993