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Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4(+) T cells

The major barrier to curing HIV-1 infection is a small pool of latently infected cells that harbor replication-competent viruses, which are widely considered the origin of viral rebound when antiretroviral therapy (ART) is interrupted. The difficulty in distinguishing latently infected cells from th...

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Detalles Bibliográficos
Autores principales: Cai, Jinfeng, Gao, Hongbo, Zhao, Jiacong, Hu, Shujing, Liang, Xinyu, Yang, Yanyan, Dai, Zhuanglin, Hong, Zhongsi, Deng, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041464/
https://www.ncbi.nlm.nih.gov/pubmed/33835029
http://dx.doi.org/10.7554/eLife.63810