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Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4(+) T cells
The major barrier to curing HIV-1 infection is a small pool of latently infected cells that harbor replication-competent viruses, which are widely considered the origin of viral rebound when antiretroviral therapy (ART) is interrupted. The difficulty in distinguishing latently infected cells from th...
Autores principales: | Cai, Jinfeng, Gao, Hongbo, Zhao, Jiacong, Hu, Shujing, Liang, Xinyu, Yang, Yanyan, Dai, Zhuanglin, Hong, Zhongsi, Deng, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041464/ https://www.ncbi.nlm.nih.gov/pubmed/33835029 http://dx.doi.org/10.7554/eLife.63810 |
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