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An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence

A high-throughput systematic evolution of ligands by exponential enrichment assay was applied to 371 putative TFs in Pseudomonas aeruginosa, which resulted in the robust enrichment of 199 unique sequence motifs describing the binding specificities of 182 TFs. By scanning the genome, we predicted in...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Sun, Wenju, Fan, Ligang, Hua, Canfeng, Wu, Nan, Fan, Shaorong, Zhang, Jilin, Deng, Xin, Yan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041468/
https://www.ncbi.nlm.nih.gov/pubmed/33779544
http://dx.doi.org/10.7554/eLife.61885