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Efficient hybrid de novo assembly of human genomes with WENGAN

Generating accurate genome assemblies of large, repeat-rich human genomes has proved difficult using only long, error-prone reads, and most human genomes assembled from long reads add accurate short reads to polish the consensus sequence. Here we report an algorithm for hybrid assembly, WENGAN, that...

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Detalles Bibliográficos
Autores principales: Di Genova, Alex, Buena-Atienza, Elena, Ossowski, Stephan, Sagot, Marie-France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041623/
https://www.ncbi.nlm.nih.gov/pubmed/33318652
http://dx.doi.org/10.1038/s41587-020-00747-w