Promising potential of [(177)Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model

PURPOSE: It was previously demonstrated that radiation effects can enhance the therapy outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model was used to investigate the effect of [(177)Lu]Lu-DOTA-folate as an immune stimulus to enhance anti-CTLA-4 immunotherapy...

Descripción completa

Detalles Bibliográficos
Autores principales: Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041666/
https://www.ncbi.nlm.nih.gov/pubmed/33078260
http://dx.doi.org/10.1007/s00259-020-05054-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041666/
https://www.ncbi.nlm.nih.gov/pubmed/33078260
http://dx.doi.org/10.1007/s00259-020-05054-9

Ejemplares similares