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Promising potential of [(177)Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model
PURPOSE: It was previously demonstrated that radiation effects can enhance the therapy outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model was used to investigate the effect of [(177)Lu]Lu-DOTA-folate as an immune stimulus to enhance anti-CTLA-4 immunotherapy...
Autores principales: | Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041666/ https://www.ncbi.nlm.nih.gov/pubmed/33078260 http://dx.doi.org/10.1007/s00259-020-05054-9 |
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