Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy

PURPOSE: The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent...

Descripción completa

Detalles Bibliográficos
Autores principales: Guzik, Patrycja, Benešová, Martina, Ratz, Magdalena, Monné Rodríguez, Josep M., Deberle, Luisa M., Schibli, Roger, Müller, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041685/
https://www.ncbi.nlm.nih.gov/pubmed/33063250
http://dx.doi.org/10.1007/s00259-020-04980-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041685/
https://www.ncbi.nlm.nih.gov/pubmed/33063250
http://dx.doi.org/10.1007/s00259-020-04980-y

Ejemplares similares